Protein-Folding

MegaFold: an Open-Sourced AlphaFold-3 Training System

This blog presents a deep analysis of Alpha-Fold 3 (AF3) training pipelines, pinpointing their inefficiencies and introduces MegaFold: an end-to-end training system for AF3 that addresses the aforementioned issues. 

October 3, 2025 10 minutes